Seneca,SC #1130 My Store
Store Hours
  • Mon-Sat: 6:00am - 10:00pm
  • Sun: 8:00am - 8:00pm

Store Number (864) 886-0633

Pro Desk (864) 985-7964

Manager Michael S.

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Store Address:
  • 1614 Sandifer Blvd
  • Seneca, SC 29678

Store Details

You can find the Seneca, SC Home Depot conveniently located near Chick-fil-A, so stop in and check out our deals on the best products from your favorite brands.

There's a lot to be said for getting a job done right the first time, so whether you're fixing a flagpole, planting petunias or replacing crown molding, you've come to the right place. As a dedicated part of the Seneca community, we're proud to give back by being members of the Oconee County Chamber of Commerce. Next time you're in the neighborhood, stop in and see us.

Welcome to the Seneca Home Depot where we look forward to helping you with your home improvement needs.

Your Seneca Store Team

Scary Good Deals on Halloween Decorations

Transform your home into a spooky haunted house this Halloween! Our large selection of zombies, witches and indoor/outdoor lights are the perfect Halloween decorations for an unforgettable night. Visit The Home Depot for the best deals on all things Halloween.

Up Your Game and Save on Tailgating Supplies

Tailgate in style while you celebrate College Game Day. This fall, shop dozens of deals at The Home Depot, from grills to tents, seating and much more! Whether you need a cooler or a canopy, we've got you covered. See you at the game!