Picayune #2915 My Store
Store Hours
  • Mon-Sat: 6:00am - 9:00pm
  • Sun: 8:00am - 7:00pm

Store Number (601) 749-2180

Pro Desk (601) 799-4002

Manager Tammy H.

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Store Address:
  • 2000 Hwy 43 South
  • Picayune, MS 39466

Store Details

Hi, how are y'all today? Thanks for shopping your Picayune Home Depot. At the Picayune, MS Home Depot, we can handle all your home improvement needs, whether you're replacing your air filters or a bathroom sink. 

You can find us at Hwy. 43 S., right off the interstate next to Walmart. We're proud to be your community satellite store, and we'll make sure you have everything you need for your next home project. We support the City of Picayune, Habitat for Humanity, Pearl River High School and many others.

Stop by The Home Depot today for help with your next DIY venture.

Your Picayune Hardware Store Team

Christmas Trees and Decorations for Every Room

Deck the halls with ease with our wide range of fresh cut and artificial Christmas trees from The Home Depot! Find beautiful and high-tech Christmas decorations to complement your one-of-a-kind tree online or at your nearest Home Depot store today.