Otay Mesa #1034 My Store
Store Hours
  • Mon-Sat: 6:00am - 10:00pm
  • Sun: 7:00am - 8:00pm

Store Number (619) 428-8662

Pro Desk (619) 690-8357

Manager Richard T.

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Store Address:
  • 950 Dennery Road
  • San Diego, CA 92154

Store Details

Here at The Home Depot, we have the widest selection of home improvement products and services in San Diego, CA. Whether you need nuts and bolts, a new bathroom sink, or state-of-the-art appliances, you can find everything you need right here under one roof. We are located in South San Diego near the U.S.-Mexico Border off the 805 Freeway, so stop in today and find out why we're so much more than a hardware store.

We love being part of the San Diego community, and to share the love, we support our veterans and hardworking families. We are excited to service the San Diego South Bay community and look forward to seeing you in my store. Let us know how we can help you with your next project.

Your Otay Mesa Store Team

Scary Good Deals on Halloween Decorations

Transform your home into a spooky haunted house this Halloween! Our large selection of zombies, witches and indoor/outdoor lights are the perfect Halloween decorations for an unforgettable night. Visit The Home Depot for the best deals on all things Halloween.

Up Your Game and Save on Tailgating Supplies

Tailgate in style while you celebrate College Game Day. This fall, shop dozens of deals at The Home Depot, from grills to tents, seating and much more! Whether you need a cooler or a canopy, we've got you covered. See you at the game!