Otay Mesa #1034 My Store
Store Hours
  • Mon-Sat: 6:00am - 9:00pm
  • Sun: 7:00am - 8:00pm

Store Number (619) 428-8662

Pro Desk (619) 690-8357

Manager Richard T.

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Store Address:
  • 950 Dennery Road
  • San Diego, CA 92154

Store Details

Here at The Home Depot, we have the widest selection of home improvement products and services in San Diego, CA. Whether you need nuts and bolts, a new bathroom sink, or state-of-the-art appliances, you can find everything you need right here under one roof. We are located in South San Diego near the U.S.-Mexico Border off the 805 Freeway, so stop in today and find out why we're so much more than a hardware store.

We love being part of the San Diego community, and to share the love, we support our veterans and hardworking families. We are excited to service the San Diego South Bay community and look forward to seeing you in my store. Let us know how we can help you with your next project.

Your Otay Mesa Store Team

Christmas Trees and Decorations for Every Room

Deck the halls with ease with our wide range of fresh cut and artificial Christmas trees from The Home Depot! Find beautiful and high-tech Christmas decorations to complement your one-of-a-kind tree online or at your nearest Home Depot store today.